The New York Giants (1-1) will do their best to defy oddsmakers when they square off against the San Francisco 49ers (2-0) on Thursday, September 21, 2023 as a 10-point underdog. The point total is set at 44 points for the outing.

The recent betting insights and trends for the 49ers can be found below before they meet the Giants. As the Giants ready for this matchup against the 49ers, check out their betting trends and insights.

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49ers vs. Giants Odds, Spread, Over/Under

Check out the odds, spread and over/under for this matchup posted at different sportsbooks.

Favorite Total San Francisco Moneyline New York Moneyline
BetMGM 49ers (-10) 44 -550 +400 Bet on this game with BetMGM
FanDuel 49ers (-10.5) 44 -550 +410 Bet on this game with FanDuel

Other Week 3 Odds

San Francisco vs. New York Game Info

  • When: Thursday, September 21, 2023 at 8:15 PM ET
  • Where: Levi's Stadium in Santa Clara, California
  • TV Info: Amazon Prime Video
  • Live Stream: Watch this game on Fubo!

49ers vs. Giants Betting Insights

  • San Francisco covered the spread 11 times in 17 games last year.
  • The 49ers covered every time (1-0) as a 10-point favorite or more last season.
  • Out of 17 San Francisco games last year, nine hit the over.
  • New York had 13 wins in 17 games against the spread last year.
  • The Giants won each of their two games last year when playing as at least 10-point underdogs.
  • New York had seven of its 17 games hit the over last year.

49ers Player Props

Name Pass Yds Pass TDs Rush Yds Rush TDs Rec Yds Rec TDs
George Kittle - - - - 43.5 (-111) -
Christian McCaffrey - - 78.5 (-115) - 30.5 (-111) -
Brock Purdy 228.5 (-115) - 7.5 (-115) - - -
Deebo Samuel - - 14.5 (-115) - 53.5 (-111) -

Payouts above are for the "over" bet.

Giants Player Props

Name Pass Yds Pass TDs Rush Yds Rush TDs Rec Yds Rec TDs
Darren Waller - - - - 45.5 (-115) -
Matt Breida - - 31.5 (-118) - 12.5 (-118) -
Parris Campbell - - - - 28.5 (-111) -
Daniel Jones 215.5 (-115) 1.5 (+170) - - - -
Darius Slayton - - - - 34.5 (-115) -
Isaiah Hodgins - - - - 31.5 (-118) -

Payouts above are for the "over" bet.

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